(intransitive) To come towards, to approach.I was standing on the corner when Nick came up and asked for a cigarette.
(idiomatic, intransitive) To emerge or become known, especially unexpectedly; to come to attention, present itself.Unless anything comes up, I'll be there every day this week.At some point in the conversation my name came up, and I readily agreed to their proposition.
(British, slang, intransitive) To begin to feel the effects of a recreational drug.I could tell from her expression she was coming up already.
(UK, Oxford University) To arrive at the university. (Compare go down, send down.)